Some passengers along the Osogbo/Ibokun road have been abducted on Tuesday.
It was also gathered that a passenger was killed in the bloody encounter.
According to Punch, the incident occurred between 7:30 and 8:00 pm near Ajebandele, a village in the Obokun Local Government area, about three kilometres to Osogbo, the state capital.
The gunmen had reportedly attacked travellers and shot dead a man, whose name is not immediately available, while an unspecified number of passengers were also abducted.
The Field Commander, Amotekun Corps in Osun, Amitolu Shittu, who was at the scene of the crime, confirmed the incident.
Amitolu said the deceased was shot dead by the attackers, whom he said carried AK-47 riffles, adding that search and rescue operation had commenced for those abducted.